PHR 561 - Drug Biotransformation and Pharmacogenetics

Institution:

Rush University

Subject:

Description:

The various types of biotransformation reactions, including all Phase I and Phase II reactions are discussed in detail. The course describes in detail the biochemistry of drug inactivation both in the liver and at extrahepatic sites and the effects of genotype on that biotransformation. Additional topics to be discussed include prodrugs and protoxins and special considerations needed when discussing the CNS, other separated compartments (e.g., certain tumors and bladder), and the influence of age, gender, hepatic induction, kidney failure, and genetic phenotypes. (2 Credits)

Credits:

2.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

WWW.RUSHU.RUSH.EDU

Phone Number:

(312) 942-7100

Regional Accreditation:

North Central Association of Colleges and Schools

Calendar System:

Quarter

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