BISC 331 - Seminar.Cancer Genomics

Institution:

Wellesley College

Subject:

Description:

Webb Cancer can be attributed to disruption of gene structure and function. Functional genomics has contributed more to the understanding and treatment of cancer in the last five years than the previous half century of oncology research. This course will provide a comprehensive study of the biological basis of malignancy from pathophysiology to the genetics of the transformed phenotype with a view to use of ge-nomics in diagnosis, prognosis and treatment directed at specific molecular targets. Topics to be discussed include pharmacogenomics, immunotherapy, tumor stem cells, RNAi, biomarkers, oncolytic viruses, nanotechnology, transcriptional profiling of both coding and non-coding RNAs, and reprogramming of epigenomic as well as epithelial-mesenchyme transition profiles. Class discussion and student pres-entation of recent original literature will be an integral part of the course. Prerequisites: 219 or 220 or by permission of the instructor Distribution: Natural and Physical Science Semester: Spring Unit: 1.0

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.wellesley.edu

Phone Number:

(781) 283-1000

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Semester

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