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			Institution:
		
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			Rensselaer Polytechnic Institute
		
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			Subject:
		
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			Description:
		
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			In this laboratory associated with CHEM-4330, students will reduce to practice the chemical and biological aspects of high-throughput screening used to discover lead molecules. Colorimetric and fluorescence plate readers will be used in 96-well plate format to generate enzyme inhibition data for small libraries of organic molecules. Students will use these inhibition data and published X-ray structural data to develop a pharmacophore model and rationalize a structure-activity relationship. Prerequisites/Corequisites: Prerequisite: CHEM 4330 or concurrent with CHEM 4330. When Offered: Fall term annually. Credit Hours: 1
		
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			Credits:
		
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			1.00
		
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			Credit Hours:
		
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			Prerequisites:
		
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			Corequisites:
		
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			Exclusions:
		
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			Level:
		
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			Instructional Type:
		
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			Lecture
		
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			Notes:
		
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			Additional Information:
		
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			Historical Version(s):
		
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			Institution Website:
		
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			Phone Number:
		
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			(518) 276-6000
		
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			Regional Accreditation:
		
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			Middle States Association of Colleges and Schools
		
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			Calendar System:
		
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			Semester
		
		
	
 
	 
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