ABio 329 - Genetics of Human Disease

Institution:

SUNY at Albany

Subject:

Description:

Four categories of the involvement of human genes in disease will be explored using specific examples to illustrate general phenomena. First, inheritance of diseases caused by single mutant alleles will be discussed. Second, the pre-disposition of specific genotypes to disease will be investigated highlighting the interplay between genes and between the genes and the environment. Third, genetic instabilities that give rise to genetic rearrangements and chromosome loss will be explored. Fourth, the genetic interplay between host and pathogen will be explored with respect to the evolution of protective mechanisms by the host and evasion by the pathogen, and how new pathogens emerge. For each category, multiple cases of specific diseases will be discussed with an emphasis on both the molecular basis of the genetic interactions and the population genetics of disease spread and persistence. The potential of modern genetic techniques to provide diagnosis and treatment of diseases will also be discussed. Prerequisite(s): A Bio 212.

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.albany.edu

Phone Number:

(518) 442-3300

Regional Accreditation:

Middle States Association of Colleges and Schools

Calendar System:

Semester

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