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Institution:
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St Lawrence University
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Subject:
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Description:
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This course focuses on the organic chemistry of drug design and on the molecular level basis of drug action. Topics include the pharmaceutical, pharmacokinetic and pharmacodynamic phases of drug action, drug targets and a survey of the drug development process from lead identification to marketed therapeutic agent. Representative pharmaceuticals are studied in depth in terms of discovery and mode of therapeutic action. Competitive, non-competitive, irreversible and mechanism-based "suicide" enzyme inhibitors; G-protein coupled receptor, ligandgated ion channel and transporter protein targeted agonists and antagonists and DNA targeted agents are covered. Prerequisite: Chemistry 222.
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Credits:
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4.00
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Credit Hours:
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Prerequisites:
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Corequisites:
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Exclusions:
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Level:
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Instructional Type:
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Lecture
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Notes:
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Additional Information:
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Historical Version(s):
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Institution Website:
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Phone Number:
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(315) 229-5011
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Regional Accreditation:
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Middle States Association of Colleges and Schools
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Calendar System:
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Semester
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