BIOLOGY 243 - Molecular Genetics

Institution:

City Colleges of Chicago-Harry S Truman College

Subject:

Description:

This course will build upon the foundations of classical mendelian genetics, and will incorporate concepts of modern genetics, including both the fundamentals and current research methods for analysis of gene structure and gene expression. The gene expression component will include positive and negative regulation of transcription and mRNA splicing and turnover. The basics of DNA recombination, repair, and transposition will be covered in relationship to cancer, evolution, and mutagenesis. Strategies for developmental regulation will be presented. Parallels between prokaryotes and eukaryotes will be drawn, and comparisons will be made between the temporal and spatial control of gene expression in vertebrates and invertebrates. Genetic engineering topics will include gene targeting and transgenesis, with applications to understanding tissue specific control of gene expression. This course will also entail population and quantitative genetics. This course will include discussion of the Genome project, identification of disease genes and an introduction to the medical application of molecular genetics including gene therapy. Writing assignments, as appropriate to the discipline, are part of course. Prerequisite: Biology 121 and Biology 122 and Chemistry 121. 2 lecture and 4 lab hours per week. 4 credit hours.

Credits:

3.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Multiple

Notes:

Additional Information:

Historical Version(s):

Institution Website:

ccc.edu/colleges/truman/pages/default.aspx

Phone Number:

(773) 907-4000

Regional Accreditation:

North Central Association of Colleges and Schools

Calendar System:

Semester

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