BIOL 2320A - Cell Fate and Lineage Decisions in Neural Development and Neurological Diseases

Institution:

Brown University

Subject:

Description:

We will explore mechanisms underlying how neuronal cell fates are established during development and how the understanding of this process may provide insight into neurological disease and therapeutic intervention. Topics: Temporal identity in neuroblast and cerebral cortex cell fate speci?cation, transcriptional control of lineage decisions in the spinal cord, the role of morphogen concentration and timing on cell fate decisions, micro RNA control of gene regulation, epigenetics, induced pluripotent stem cells, stem cell use in therapeutic approaches to intervene in neurological diseases. Primary literature will be discussed in lectures in the format of student-led, faculty-guided discussions. Enrollment limited to 20. Instructor permission required.

Credits:

1.00

Credit Hours:

Prerequisites:

Corequisites:

Exclusions:

Level:

Instructional Type:

Lecture

Notes:

Additional Information:

Historical Version(s):

Institution Website:

www.brown.edu

Phone Number:

(401) 863-1000

Regional Accreditation:

New England Association of Schools and Colleges

Calendar System:

Semester

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