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Institution:
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California Institute of Technology
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Subject:
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Chemical Engineering
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Description:
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The course introduces rational design and evolutionary methods for engineering functional protein and nucleic acid systems. Rational design topics include molecular modeling, positive and negative design paradigms, simulation and optimization of equilibrium and kinetic properties, design of catalysts, sensors, motors, and circuits. Evolutionary design topics include evolutionary mechanisms and tradeoffs, fitness landscapes, directed evolution of proteins, and metabolic pathways. Some assignments require programming (MATLAB or Python). Instructors: Arnold, Pierce.
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Credits:
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9.00
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Credit Hours:
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Prerequisites:
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Bi/Ch 110 or instructor’s permission.
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Corequisites:
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Exclusions:
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Level:
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Instructional Type:
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Lecture
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Notes:
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Additional Information:
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Historical Version(s):
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Institution Website:
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Phone Number:
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(626) 395-6811
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Regional Accreditation:
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Western Association of Schools and Colleges
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Calendar System:
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Quarter
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