A description for this course has not been provided

Prerequisite(s): University Advanced Standing. Corequisite(s): BIOL 4450. Addresses federal, local and institutional regulations on using vertebrate animals for biomedical research. Teaches and regularly practices aseptic techniques required in handling biohazardous materials including vertebrate tissues. Studies how to collect tissues and blood from vertebrate animals and process the samples for harvesting various types of cells and macromolecules. Presents common immunological techniques such as western blot analysis and ELISA. Covers how to immunize animals using appropriate adjuvant and harvest plasma from immunized animals to isolate immunoglobulin. Examines tissue typing methodologies including PCR techniques.. Course Lab fee of $150 applies.

Prerequisite(s): (MICR 2060 or MICR 3450 or ZOOL 2420) and University Advanced Standing. Explores the macromolecules, cells and organs involved in innate and adaptive immunity. Examines the development of lymphocyte repertoire, positive and negative selection of lymphocytes and the production of effector lymphocytes. Studies properties of antigens, vaccines, antigen presenting cells and the mechanisms of antigen presentation. Reviews major immunological methods for medical diagnostics and other applications. Examines causes and consequences of autoimmune and lymphoproliferative diseases and immunodeficiencies. Probes how immune response could be manipulated for cancer therapy and transplantation medicine.